Technology

GenTegra holds numerous patents for its Active Chemical Protection™ (ACP) formulation.  ACP comprises a proprietary matrix of chemicals that keep protein, DNA and RNA stable in a dry ambient state as they are exposed to conditions outside their biological micro-environments.  Our technology enables these biological macromolecules to maintain their native structure and remain functionally active. ACP is available in multiple formulas to protect biomolecules in a variety of applications and has been validated in numerous SBIR and DARPA grants.

Gentegra’s Proprietary ACP Protects Biomolecules Leading to High Quality Samples and More Accurate Results

  • When exposed to the environment (water, heat, oxygen), nucleases, and proteases, the biomolecular structures are degraded and denatured.
  • GenTegra ACP keeps proteins, RNA, and DNA stable and protects from being denatured and degraded; which allows molecules to maintain their functional structures.
  • ACP is available in multiple formulas to protect biomolecules, in a variety of applications.

Applications

COVID-19 Saliva Sampling

GTR-STM is a saliva collection device that contain the dry media, non-dilutive Active Chemical Protection™ formulation. The product is used for COVID-19 testing to improve SARS-CoV-2 viral RNA stability, and process efficiency. GTR-STM is stable for up to 50-days at ambient temperature.

Better RNAseq results

GenTegra’s Active Chemical Protection formulation provides unparalleled stability and shielding of purified RNA samples from degradation. GenTegra RNA keeps RNA stable during shipping without dry ice. Ambient shipping reduces the risk of sample loss, improves the quality of RNAseq results, and reduces overall costs.

Patient Centric Sampling

The evolution taking place in micro-sample blood collection devices is driving the creation of an entirely new paradigm in patient-centered medicine. Improved patient compliance and convenience are some of the many benefits of these new devices. GenTegra’s Active Chemical Protection technology will play a critical role to ensure the quality of samples collected and analyzed for routine clinical care and pharmaceutical clinical trials.

Coroner & Forensic Field Samples

Remote field-based collection and shipment of samples to the laboratory presents unique challenges. GenTegra’s suite of field collection card products, utilizing Active Chemical Protection technology protect DNA, RNA and small molecule samples from the hazards of environmental degradation during shipment or long-term storage.

Biobanking

GenTegra-DNA dry ambient storage technology vs. traditional freezer storage represents significant savings in cost savings, space efficiency, and lower risk of sample loss.

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